Phenanthrenes and derivatives
Medchemexpress LLC Bcr-Abl1-In-1 | 1488090-21-6 | 99.82% | C18H12F3N3O2 | 100 MG
BCR-ABL1-IN-1 is an inhibitor for ABL1 (64-515) with an IC50 of 8.7 nM. It can be utilized in research concerning diseases related to the central nervous system (CNS).
- Exhibits antiproliferative activity against mouse BaF3 cells expressing BCR-ABL with a GI50 of 69 nM and an IC50 of 75 nM.
- Inhibits the proliferation of Ba/F3-BCR-ABL1-WT cells with an IC50 of 30 nM.
Medchemexpress LLC Hypericin | 548-04-9 | MFCD00016683 | 98.2% | 504.44 | C30H16O8 | 10 MG
Hypericin is an analytical reference standard of a naturally occurring compound found in Hypericum perforatum. It is a brown to reddish-brown solid (C30H16O8; MW 504.44 g/mol) supplied at high purity for research and analytical applications, including qualitative and quantitative methods. Store and handle according to the Certificate of Analysis and applicable safety data.
- Analytical reference standard suitable for HPLC, GC, and MS
- High purity for reliable qualitative and quantitative analysis
- Brown to reddish brown solid form for ease of handling in small-batch assays
- Derived from plant source (Hypericum perforatum)
- Supplied in small sizes appropriate for analytical work
![Sigma Aldrich Fine Chemicals Biosciences Benzo[a]pyrene >=96% (HPLC) | 50-32-8 | MFCD00003602 | 5G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501848405.PNG-250.jpg)
Sigma Aldrich Fine Chemicals Biosciences Benzo[a]pyrene >=96% (HPLC) | 50-32-8 | MFCD00003602 | 5G
Benzo[a]pyrene >=96% (HPLC) | Purity: >=96% (HPLC) | Mol Wt: 252.31 | 50-32-8 | MFCD00003602 | 5G
Electron Microscopy Sciences Rosin Alcohol Stock Solution 500 ML
Rosin Alcohol solution is a prepared, ready-to-use, high quality staining solution that saves time and effort and produces consistent uniform results.
Medchemexpress LLC Aristolochic acid III | 7267-92-7 | 1 MG
Aristolochic acid III is a natural product extracted from the leaves of Aristolochia debilis, offering a purity of 85.0% and a molecular weight of 341.27. It appears as a white to light yellow solid.
- Isolated from Aristolochia debilis leaves
- Purity: 85.0%
- Molecular formula: C17H11NO7
- Molecular weight: 341.27
- Solid appearance
- Color: White to light yellow
- Stable under recommended storage conditions
eMolecules Key Organics/BIONET Malonic acid 1mg 564178357 STR00614 95 000 141-82-2 104 061 C3H4O4
Key Organics/BIONET Malonic acid 1mg 564178357 STR00614 95 000 141-82-2 104 061 C3H4O4
Medchemexpress LLC Aristolochic acid Va | 108779-46-0 | 357.27 | 5 MG
Aristolochic acid Va is a natural compound that can be isolated from Aristolochia plants. It is for research use only and not sold to patients.
- Purity: 98.74%
- Appearance: Solid
- Color: Light yellow to yellow
- Initial source: Plants Aristolochiaceae Aristolochia debilis Sieb. et Zucc.
Medchemexpress LLC Aristolochic acid C | 4849-90-5 | 327.25 | 1 MG
Aristolochic acid C is a derivative of Aristolochic acid, which functions as a phospholipase A2 (PLA2) inhibitor. This inhibition disrupts cortical microtubule arrays and root growth in *Arabidopsis*.
- Purity: 99.77%
- Appearance: solid
- Color: light yellow to orange
- Solubility in vitro: DMSO : 125 mg/mL (381.97 mM; needs ultrasonic)
- Shipping: room temperature in continental US; may vary elsewhere
- Storage: 4°C, protected from light
- Storage in solvent: -80°C, 6 months; -20°C, 1 month (protected from light)
- In vivo dissolution protocol: 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline (solubility: ≥ 2.08 mg/mL (6.36 mM); clear solution)
Sigma Aldrich Fine Chemicals Biosciences Chrysene BCR(R), certified reference material | 218-01-9 | MFCD00003698 | 20MG
Chrysene BCR(R), certified reference material | Mol Wt: 228.29 | 218-01-9 | MFCD00003698 | 20MG
Medchemexpress LLC Crizotinib hydrochloride | 1415560-69-8 | 99.7% | C21H23Cl3FN5O | 200 MG
Crizotinib hydrochloride is an orally bioavailable, selective, and ATP-competitive dual ALK and c-Met inhibitor. It also acts as a ROS proto-oncogene 1 (ROS1) inhibitor, demonstrating effective tumor growth inhibition.
- Inhibits tyrosine phosphorylation of NPM-ALK and c-Met in cell-based assays
- Potently prevents cell proliferation by inducing G(1)-S-phase cell cycle arrest and apoptosis
- Causes marked regression of large established tumors in preclinical models
- Demonstrates a significant dose-dependent reduction of CD31-positive endothelial cells
- Leads to marked inhibition of phosphorylated c-Met, Akt, Erk, PLCλ1, and STAT5 levels
Electron Microscopy Sciences Rosin Alcohol Working Solution 500 ML
Rosin Alcohol solution is a prepared, ready-to-use, high quality staining solution that saves time and effort and produces consistent uniform results.